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  • Cutaneous histiocytosis is an uncommon condition in dogs. It is a non-cancerous increase in the number of reactive cells (histiocytes) caused by an immune system dysfunction. It generally manifests as multiple bumps and nodules confined to the dog's skin. The clinical signs, diagnosis, and treatment of this condition are explained in this handout.

  • Skin cancers are common in cats, but cutaneous lymphoma is relatively uncommon. Less than 2% of lymphoma cases in cats occur in the skin. As the disease progresses, the skin becomes thickened, reddened, ulcerated, and may ooze fluid. The most common locations to find lesions include the junction between mucus membranes and the skin. Unfortunately, feline cutaneous lymphoma is considered incurable. Surgical removal can be attempted for solitary lesions, although the tumor often returns to the area or will have spread elsewhere in the body already

  • Systemic lymphoma is a very common cancer in dogs, but the cutaneous form is quite rare. Current statistics suggest that cutaneous lymphoma accounts for only about 5% of canine lymphoma cases. The disease can present in a variety of lesions, including ulcers, nodules, red patches, and areas of hair loss and skin scaling. Because not very much is known about canine cutaneous lymphoma, there are no standard treatment protocols and the prognosis is poor.

  • Cutaneous papillomatosis is the development of papillomas (non-cancerous growths, or warts) caused by the papillomavirus and affects many pet birds. Commonly affected species are finches, canaries, cockatiels, budgerigars, and African grey parrots. The clinical signs and treatment for this condition are explained in this handout.

  • Cuterebra are botflies that spend the larvae stage of their lifecycle within rodent or rabbit hosts and can accidentally infect dogs. They enter through the nose, mouth or a skin wound. They usually develop a cyst under the skin that can be located as it enlarges and often a breathing hole can be seen. The larva (warble) will leave the dog when it is ready to form a pupa but it will often leave behind a secondary bacterial skin infection or abscess in the empty cyst. Rarely, the larva/cuterebra migrate aberrantly through the dog causing inflammation and damage to different tissues, including the brain and eyes, and even potentially cause a severe systemic inflammatory response. Treatment depends on what damage has been done and can include removal of the warble, debridement or removal of the cyst, antibiotics and symptomatic and supportive treatment of the results of aberrant migration. Prognosis is generally good if only the skin is involved. Cuterebra infection can not be prevented easily, so monitoring the dog regularly for signs is important.

  • Cuterebra is the scientific name for the North American rabbit or rodent botfly. Cats are accidental hosts of Cuterebra larvae, and they are rarely evident from external skin inspection. A hole enlarges when the warble has matured, often leading to an infected empty cyst. Treatment depends on when the condition is discovered, and in many cases, antibiotics are used to treat secondary infections.

  • In cats, diseases of the lower urinary tract (bladder and urethra) are often grouped under the term feline lower urinary tract disease (FLUTD). Typical signs in cats with FLUTD are those of inflammation and irritation of the lower urinary tract. There are many potential causes of FLUTD, and diagnosis is based on assessing clinical signs and laboratory testing. There is no universal treatment for FLUTD. Each case has to be investigated to determine the underlying cause, and then the treatment has to be tailored to the individual cat.

  • Cysts are hollow spaces within tissues that contain either a liquid or a solidified material. Some breeds have a tendency to develop certain types of cysts. Accurate diagnosis relies upon microscopic examination of a piece of tissue. The most common treatment for cysts is surgical removal. It is important to prevent your pet from rubbing, scratching, or otherwise bothering the cysts or the surgical site.

  • Cytauxzoonosis is an often-fatal disease caused by a tick-borne protozoan parasite, typically found in bobcats. It is more commonly seen in the southern United States but is spreading with tick migration. It can cause anorexia, lethargy, respiratory difficulty, anemia, and jaundice. Diagnostic testing, treatment options, and preventives are described in this handout. This disease is not transmissible to dogs or humans.

  • Cytology is a useful tool to often diagnose abnormal lumps on your pet's body as well as evaluation of fluid samples and tissue surfaces. It is relatively simple and inexpensive but can provide a lot of information. Depending on results, further tests may be indicated to best help your pet.